Multivariate logistic regression analysis was performed using the following variables as covariates (Table 2): age, sex, baseline eGFR, serum albumin level, history of diabetes mellitus, hypertension, congestive heart failure requiring admission, liver cirrhosis, or cancer, total volume of radiocontrast agent, and the use of ACE inhibitors, ARBs or statins. The gene discussed is ACE; the disease is Hypertension.