Finally, we observed that Clu also binds to (i) late apoptotic Jurkat cells (induced by etoposide or an anti-Fas mAb) (Figure 1d), (ii) apoptotic murine thymocytes (Supplementary Figure S1A), and (iii) tumor cells either irradiated or treated with etoposide (Supplementary Figure S1B), demonstrating that the binding of Clu to late apoptotic cells is not dependent on the cell type or on the apoptosis-inducing signal. Here, CLU is linked to neoplasm.