In this report we examined cell death following anti-VEGF-A treatment in Ins2Akita diabetic8 and JR5558 spontaneous choroidal neovascularization (CNV) mice.9 We established that VEGF-A antagonists also accelerate neuronal apoptosis in these models, findings that may have implications for treating ocular neovascular disease with anti-VEGF drugs. Here, VEGFA is linked to choroidal neovascularization.