Resveratrol, moreover, potentiated the antitumor effects of 5-fluoruracyl (5-FLU) on CRC cells enhancing their chemosensitization and attenuating the drug resistance: the mechanism involved the suppression of EMT phenotype, with the upregulation of intercellular junctions and E-cadherin, and the downregulation of NF-κB and vimentin (43). This evidence concerns the gene VIM and colorectal carcinoma.