Resveratrol inhibited, in a dose-dependent manner, EMT of pancreatic cancer cells, by suppressing both the PI3K/AKT/NF-κB pathway and the EMT-related gene expression (E-cadherin, N-cadherin, vimentin, MMP-2, and MMP-9), pivotal for cancer cell motility and metastasis (52, 53). This evidence concerns the gene AKT1 and familial pancreatic carcinoma.