BRCA1 and peritoneum cancer: BRCA1+ carrier refers to the women who tested positive for a pathogenic BRCA1 mutation; BRCA2+ refers to the women who tested positive for a pathogenic BRCA2 mutation; and BRCAx refers to the women who tested negative for the mutations in BRCA1, BRCA2, and p53, with two or more first or second degree relatives affected with primary in situ or invasive breast, ovarian, fallopian tube, or peritoneal cancer, and at least one person must have negative test result.