Comparable to other egcSEs, SElO selectively stimulates T cells via the Vβ region of the T cell receptor (Jarraud et al., 2001; Thomas et al., 2009) and displays an ability to induce apoptosis in a broad panel of human tumor cells in a nitrous oxide and cytokine dependent mechanism manner (Terman et al., 2013). The gene discussed is SELENOO; the disease is neoplasm.