MAPT and Parkinson disease: To clarify the association found between PD and the MAPT H1 variation and to assess whether any of the H1 subclades previously described (Myers et al., 2005; Pittman et al., 2005) could be influencing PD risk or motor phenotypes, we performed a haplotype association study comparing MAPT subhaplotype frequencies between the different group of patients and controls.