Given the convergent data indicating a role of MAPT locus in PD, recent lines of research have moved to refine the potential effect of H1 haplotype into phenotypic traits of the malady (Huang et al., 2015; Davis et al., 2016; Wang et al., 2016), such as the progression of cognitive deficits (Williams-Gray et al., 2009; Seto-Salvia et al., 2011) and motor clinical subtype (Di Battista et al., 2014). Here, MAPT is linked to Parkinson disease.