Functional deficiency of CDR1as can upregulate miR-7 expression and may lead to the downregulation of AD-relevant targets, such as ubiquitin protein ligase A (UBE2A; Bingol and Sheng, 2011; Lonskaya et al., 2013; Lukiw, 2013). Here, LINC00632 is linked to Alzheimer disease.