Moreover, DLBCL patients with co-expression of PD-L1 and p-AKT had the worst 5 years OS (P=0.030, Figure 2F) compared to patients with single positive or both negative expression of PD-L1 and p-AKT, but not 3 years OS (P=0.056, Figure 2C). Here, AKT1 is linked to diffuse large B-cell lymphoma.