In a study of a cohort of consanguineous Turkish families with moderately severe inherited OI, Alanay et al. (2010) found mutations in FKBP10 and determined that FKBP10 mutations affect type I procollagen secretion, identifying a previously unrecognized mechanism in the pathogenesis of OI [10]. Here, FKBP10 is linked to osteogenesis imperfecta.