MKI67 and neoplasm: Interestingly, the proliferation marker Ki-67 was ~75% lower in the tumor cell compartment of the Dox-treated tumors compared to untreated tumors (p<0.01); whereas, Ki-67 staining was ~2-fold higher in the stromal compartments of Dox-treated tumors compared to untreated tumors (p<0.05, Supplementary Figure 2).