Changing strategy, Bevacizumab, a monoclonal antibody able to detect VEGF, was labeled with IRDye800CV, a near infra-red fluorophore (Bevacizumab-IRD800), and tumor uptake was evaluated in human xenograft-bearing athymic mice (injected with ovarian cancer cell line A2780, expressing high level of VEGF) during 1 week after tracer injection [54]. Here, VEGFA is linked to ovarian cancer.