In this study, we assessed the potential tumor/metastasis suppressor functions of PG in OVCAs, using the normal ovarian cell line IOSE-364 and OVCA cell lines OV-90 (PG and E-cadherin positive, mp53 expressing), ES-2 (PG and E-cadherin negative, N-cadherin positive and mp53 expressing), ES-2-PG (ES-2 transfectants expressing PG), ES-2-E-cad (ES-2 transfectants expressing E-cadherin) and ES-2-shN-cad (ES-2 cells in which N-cadherin has been knocked down). Here, CDH2 is linked to neoplasm.