We have shown that PG interacted with mp53 in several carcinoma cell lines and they both associated with promoters of a number of p53 target genes including tumor suppressors SFN (14-3-3s) and NME1and the oncogenic genome organizer SATB1. Furthermore, these associations were concurrent with reduced growth, migration and invasion [17,18]. The gene discussed is SATB1; the disease is neoplasm.