Thus, H11 may also be potentially beneficial for other IL-11-based therapies such as drug-induced hepatotoxicity [43], autoimmune encephalomyelitis (EAE) (the mouse model of multiple sclerosis MS) [44], infertility dependent on the deficiency of IL-11Rα [45] and in amelioration of cardiac fibrosis after myocardial infarction [46]. Here, IL11RA is linked to multiple sclerosis.