Similarly, CTHRC1 was found to be significantly up-regulated in pRCC, but not in ccRCC, and the survival analysis showed significant poor overall survival for the high CTHRC1 expression group (log-rank test, p-value = 0.013 and 0.001, and adjusted p-value 0.053 and < 0.001 for ccRCC and pRCC, respectively). Here, CTHRC1 is linked to nonpapillary renal cell carcinoma.