CASP1 and acute myeloid leukemia: The results show that the enhancement of apoptosis and therefore total cell death in ex vivo AML blasts was abrogated by the specific caspase 3 inhibitor DEVD-CHO [29], but the caspase 1 inhibitor Z-WEHD-fmk [30] had only a minor effect (Table 2A, marked decreases are bolded).