The proposed common pathophysiological basis between cancer and CVDs [65–68] is strengthened by the role of lncRNAs such as MALAT1 [29, 44], p21 [49, 60], ANRIL [38, 49, 60], and HOTAIR [39, 54] in the development of cancer as well as in CVDs. This evidence concerns the gene MALAT1 and cancer.