Recently, the adaptor protein endoplasmic reticulum IFN stimulator (STING, also known as MITA/ERIS), along with MAVS and TBK1, were identified for their contribution to STAT6 activation during viral infection with Semiliki Forest virus and herpes simplex virus 1 (HSV-1) (58). The gene discussed is MAVS; the disease is viral infectious disease.