In fact, it has been demonstrated that out of the 135 patients with SCLC screened, 37 (27 %) had PD-L1 + tumors and of 16 treated with pembrolizumab (Pembrolizumab 10 mg/kg every 2 weeks for up to 2 years or until confirmed progression or unacceptable toxicity), 4/16 (25 %) evaluable patients had a partial response. Here, CD274 is linked to small cell lung carcinoma.