AGO2 and Miyoshi myopathy: Interestingly, if the comparison is done between AGO2-sh72 treated My5.LV cells and AGO2 cDNA treated My5.LV cells, majority of the miRNAs were increased (Fig. 5c and Additional file 1: Figure S5D), suggesting that the stabilities of miRNAs in MM cells are associated with the intracellular levels of AGO2.