Unsupervised hierarchical clustering (Fig. 1) of the microarray data comparing HC, SjS, SLE and RA CD14+ monocytes showed p SjS (8/12, 66.7 %), s SjS (3/6, 50 %), and SLE (7/10, 70 %) samples formed a cluster. This evidence concerns the gene HSPG2 and systemic lupus erythematosus.