INSR and polycystic ovary syndrome: In addition, in the women with PCOS, insulin levels was lower in the women with the INSR NsiI "NN" genotype compared with those with the "Nn + nn" genotypes and the difference remained significant after adjustment for age and BMI (n= 18, n= 17, respectively; 13.25 ± 1.13 versus 18.61 ± 1.14, p= 0.045).