Moreover, in non-Hodgkin's lymphoma (NHL), the effects of 2-DG alone could be further potentiated by the addition of the BH3 mimetic ABT-737 that targets the remaining BCL-2 family members, thereby sensitising NHL cells to both BAK- and BAX-dependent apoptosis (Meynet et al, 2012). Here, BAX is linked to non-Hodgkin lymphoma.