LARS1 and infection: We propose that glycoconjugates with terminal Man-N-glycans in the NEJTeg are likely to interact with DCs and macrophages via Man-specific CLRs at the early stages of infection, impairing the DC function and augmenting the M2a population in the peritoneal cavity, as seen with adult F. hepatica homogenate or ES fractions [23–25], contributing to the development of the biased Th2 that is elicited in the mammalian host [25,36].