INS and Hyperglycemia: Levels of blood glucose (Fig. 2a–d) and plasma insulin (Fig. 2e–h) in overnight-fasted or randomly fed states were unaffected in both 12-week-old C2αD1268A/WT male and female mice, although a slight hyperglycaemia and a tendency to hyperinsulinaemia was observed in male mice under fed conditions (Fig. 2c, g).