Importantly, CXCL10 and CCL20 expressions were decreased in the psoriasis-like lesions in the absence of p204 (Fig. 6F–I), which was accompanied by a decrease in the phospho-p65 level and inhibition of p65 nuclear translocation in epidermal cells (Fig. 7A,B). This evidence concerns the gene CXCL10 and psoriasis.