Although tumor buds of breast carcinoma display higher levels of vimentin [63], and oral squamous cell carcinoma tumor buds have significantly upregulated fibronectin [116], only a fraction of tumor samples of oral squamous cell carcinoma underwent a full ‘cadherin switch’ from E-cadherin to N-cadherin [67]. This evidence concerns the gene FN1 and oral cavity squamous cell carcinoma.