Interestingly, the molecular players mediating these beneficial effects, namely SIRT1, AMPK, and PGC-1α, are common in the different models of myopathies (metabolic and DMD), and this reinforces the notion that improvement of mitochondrial functions is a key element to account for RSV’s beneficial effects. The gene discussed is PPARGC1A; the disease is Duchenne muscular dystrophy.