Recently, it has been reported that additional knockout of Ccr6 into ApcMin/+ mice, a mouse model of familial adenomatous polyposis, diminishes the number and size of their intestinal adenomas, suggesting that the intestinal tumorigenesis driven by the CCL20–CCR6 interaction may be promoted by macrophages recruited into the intestine [118]. Here, CCR6 is linked to Familial adenomatous polyposis.