Further investigation of carrageenan-induced peritonitis model revealed that nerolidol decreased the levels of polymorphonuclear cells and tumor necrosis factor (TNF-α) in peritoneal lavage as well as interleukin 1 beta (IL-1b) in LPS-stimulated, peritoneal macrophages (Table 4) [103]. The gene discussed is IL1B; the disease is peritonitis.