GATA3 and inflammatory response: 2006). GATA3 is crucial in inducing allergic airway inflammation (Barnes 2008); although rs72779075 is located 725 kb downstream of GATA3, it may tag variants that influence symptoms of airway inflammation and thus may motivate smokers to quit. Alternatively, RP11‐575N15 may have an unidentified function. Transcripts produced from pseudogenes may, for example, regulate the effects of microRNAs on their targets by competing for microRNA binding (Swami 2010).