In a study on disease recurrence in CRC patients who went through curative surgery, a reverse correlation between Wnt-target genes (Lgr5,Ascl2,Axin2,Dkk1, andApcdd1) levels and disease recurrence was found, suggesting that elevated expression of Wnt-target genes is associated with good prognosis54. Here, LGR5 is linked to colorectal carcinoma.