IGHE and Alzheimer disease: At the moment it can be stated that AIT, in compliance with all necessary conditions for its implementation, can be really effective and safe treatment option for a specific group of patients with IgE-mediated AD with sensitization to aeroallergens (in particular, to HDMA, grass and plants pollen allergens) or in severe uncontrolled form of AD when the benefits of using AIT exceed the risk of adverse effects occurrence.