Current diagnostic criteria for sCJD rely on clinical features, the results of electroencephalography and magnetic resonance imaging, and the presence of 14‐3‐3 protein in the cerebrospinal fluid (CSF).1, 2 These tests are not specific for CJD, and none is able to detect all forms of CJD.3, 4. Here, YWHAQ is linked to Creutzfeldt Jacob disease.