This ambiguity highlights the need to further investigate the ability of EGFR and VEGFR to distinguish between normal and malignant pancreatic tissue, especially since fluorescence-labeled contrast agents directed at EGFR and VEGF, including bevacizumab-IRDye800CW, cetuximab-IRDye800CW, and panitumab-IRDye800CW, are in various stages of clinical trials for clinical use in several other types of cancer [15]. This evidence concerns the gene VEGFA and cancer.