For tumor-specific imaging of periampullary adenocarcinoma, VEGFR2 (21 points), CEA (20 points), cMET (19 points), EGFR (18 points), and integrin αvβ6 (18 points) were categorized as potential targets by the TASC scoring system. This evidence concerns the gene CEACAM5 and periampullary adenocarcinoma.