PLOD1 and hypoalphalipoproteinemia, primary, 1: The association between FHA and PCOM has been poorly described in the literature and the studies are heterogeneous (variable diagnostic criteria for FHA and PCOM, confusion between hypogonadotropic hypogonadism and FHA, inconsistent LH level, small series or case reports) and as a result, the conclusions are contradictory [17–25].