Compared with the blank control group, the tumour volumes were significantly decreased in STAT3 group [624.21±54.21 compared with 1421.57±241.06 mm3], CDDP group [603.72±82.41 compared with 1421.57±241.06 mm3] and combination group [376.18±68.91 compared with 1421.57±241.06 mm3] respectively. Here, STAT3 is linked to neoplasm.