The two fusion constructs were then co-transfected, alone or in combination, together with a reporter construct containing five GAL4 binding sites upstream of a minimal TATA box controlling the firefly luciferase reporter gene (pG5LUC) into neuroblastoma SK-N-BE(2)C (Fig. 1C) and HeLa cells (Fig. 1D). This evidence concerns the gene LGALS4 and neuroblastoma.