IDH1, ASXL1, FLT3-ITD, MLL-PTD, CEBPA, NRAS, TET2, DNMT3A, KIT, TP53, UTX, SF3B1, SRSF2, SETBP1, RUNX1 and EZH2 mutations were detected in 319 individuals with AML using DNA sequencing. This evidence concerns the gene EZH2 and acute myeloid leukemia.