IGF1R and cancer: miR-16 has an important role in regulating apoptosis in different cancer types including lung, breast, liver, glioblastoma, and squamous cell carcinoma through targeting FEAT/METTL13 [275], RPS6KB1, IGF1R [276], CCND1 [277], BCL2 [278], RECK, and/or SOX6 [279].