Validated miR-155 target genes are present in multiple pathways associated with cancer and cancer progression, including EMT (SMAD5), proliferation (SOCS1, INPP5D, and CSF1R), block of differentiation (SPI1, CEBPB), and apoptosis (CASP3, FADD, APAF1, and FOXO3A) [359,360,361,362,363,364,365,366,367]. This evidence concerns the gene INPP5D and cancer.