The latter identified several risk-associated loci with genetic susceptibility, including the SNPs PSCA rs2976392 (strong linkage disequilibrium with rs2294008), PLCE1 rs2274223, ZBTB20 rs9841504, and PTGER4/PRKAA1rs13361707.[19–21] MUC1 rs9841504 and TYMS rs2790 have been recognized as risk alleles in similar studies of gastric cancer.[25, 26] However, results have not always been consistent, possibly owing to varying hereditary traits.[22–25]. This evidence concerns the gene PTGER4 and gastric cancer.