IL10 and chronic rhinosinusitis without nasal polyps: Likewise, IL-10 (Fig. 3), a Treg related cytokine, was decreased in NP (median 41 pg/ml, range 8–72 pg/ml) compared to controls (median 73 pg/ml, range 31–158 pg/ml; p < 0.001) as well as to CRSsNP (median 74 pg/ml, range 20–118 pg/ml; p < 0.001).