The expression of Tim-3 was upregulated in LMVsmiRCtrl-treated AML cells (P < 0.05 versus veh; Figure 5(b)) but was downregulated in LMVsmiR34a-treated AML cells (P < 0.05 versus veh; Figure 5(b)). This evidence concerns the gene HAVCR2 and acute myeloid leukemia.