Interestingly, high-glucose treatment of endothelial cells decreased ets-1 expression.37 Hence, the alteration in miR-126 expression could explain that improved glycemic control in diabetes mellitus leads to reduced thrombogenicity.9 Vice versa, glycation products were reported to increase TF expression.9,38 Our results show an important relationship between upregulation of miR-126 levels and reduction in TF-associated thrombogenicity. This evidence concerns the gene ETS1 and diabetes mellitus.