Bejar's mutation score [14] takes into account mutations in 5 genes, namely TP53, EZH2, ETV6, RUNX1 and ASXL1, and patients with bone marrow fibrosis grade 2 or higher had higher Bejar's scores (p = 0.006, Mann-Whitney), but not higher IPSS-R scores. Here, RUNX1 is linked to primary myelofibrosis.