Additionally, the calculated overall positive (PPV) and negative predictive values (NPV) across the investigated cancer entities (NSCLC, CRC and PaCa) for EpCAM+CD147+ taMPs distinguishing CRC and other neoplasia from healthy controls and from thyroid nodules (struma nodosa). The gene discussed is BSG; the disease is permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome.