CDH1 and neoplasm: During EMT tumor cells acquire a mesenchymal, migratory and invasive phenotype by losing their intercellular junctions (i.e., adherens junctions, tight junctions, desmosomal junctions and also, partially, gap junctions), typical molecular markers (E-cadherin, cytokeratins), cytoskeletal organization (changes in microtubules, actin filaments, β-filamin or talin), apical/basolateral polarity and, finally, contact inhibition [27, 29–32].