In 2009, genome-wide associations studies identified three single nucleotide polymorphisms (SNPs) within DNA region containing interferon lambda 3 (IFNL3) and IFNL4 genes, rs12979860, rs809917 and rs12980275, as prognostic factors of HCV-related liver disease, strongly associated with treatment-induced and spontaneous clearance of HCV [2–4]. The gene discussed is IFNL3; the disease is liver disorder.