In accordance with recent reports of Tau phosphorylation at the phospho-PHF-Tau (AT8) epitope in the cortex and striatum of human HD brains,23 we observed the presence of AT8 neuronal inclusions in the granule cell layer (GCL) and hilus of HD hippocampal sections but not of control (CT; Figures 1a–e). The gene discussed is MAPT; the disease is Huntington disease.