TLR1 and mantle cell lymphoma: These results suggest that local stimulation of TLR1/2 or TLR5 may contribute to the constitutive activation of NF-κB observed in MCL,[43] behaving thus similarly to the B-cell activation factor BAFF released by stromal cells, which was shown to enhance survival, migration and drug resistance of MCL cells via NF-κB activation.[26]